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splinter proof
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splinterproof
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A novel target enrichment strategy in next-generation sequencing through 7-deaza-dGTP-resistant enzymatic digestion.
BMC Res Notes. 2020 Sep 18;13(1):445. doi: 10.1186/s13104-020-05292-y.
BMC Res Notes. 2020.
PMID: 32948245
Free PMC article.
It combined 7-deaza-2'-deoxyguanosine 5'-triphosphate (c(7)dGTP)-involved primer extension, splinter-assisted intracellular cyclization, c(7)dGTP)-resistant enzymatic digestion, and two-phase rolling cycle amplification. ...TEEDseq achieved an HBV on-target rate of 3.31 0. …
It combined 7-deaza-2'-deoxyguanosine 5'-triphosphate (c(7)dGTP)-involved primer extension, splinter-assisted intracellular cyclizati …
Targeted locus amplification to detect molecular markers in mantle cell and follicular lymphoma.
Genuardi E, Klous P, Mantoan B, Drandi D, Ferrante M, Cavallo F, Alessandria B, Dogliotti I, Grimaldi D, Ragaini S, Clerico M, Lo Schirico M, Saraci E, Yilmaz M, Zaccaria GM, Cortelazzo S, Vitolo U, Luminari S, Federico M, Boccadoro M, van Min M, Splinter E, Ladetto M, Ferrero S.
Genuardi E, et al.
Hematol Oncol. 2021 Aug;39(3):293-303. doi: 10.1002/hon.2864. Epub 2021 Mar 31.
Hematol Oncol. 2021.
PMID: 33742718
Free PMC article.
Clinical Trial.
Moreover, MRD by BCL2-TLA reached good sensitivity levels also in FL and was predictive of a primary refractory case. In conclusion, this study offers the proof of principle that TLA is a promising and reliable NGS-based technology for the identification of novel molecular …
Moreover, MRD by BCL2-TLA reached good sensitivity levels also in FL and was predictive of a primary refractory case. In conclusion, this st …
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Genetic Screening Test to Detect Translocations in Acute Leukemias by Use of Targeted Locus Amplification.
Alimohamed MZ, Johansson LF, de Boer EN, Splinter E, Klous P, Yilmaz M, Bosga A, van Min M, Mulder AB, Vellenga E, Sinke RJ, Sijmons RH, van den Berg E, Sikkema-Raddatz B.
Alimohamed MZ, et al.
Clin Chem. 2018 Jul;64(7):1096-1103. doi: 10.1373/clinchem.2017.286047. Epub 2018 May 24.
Clin Chem. 2018.
PMID: 29794109
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Restaging procedures, criteria of response, and relationship between pathological response and survival.
Splinter T, Denis L.
Splinter T, et al.
Semin Oncol. 1990 Oct;17(5):606-12.
Semin Oncol. 1990.
PMID: 2218573
Review.
The first priorities for upfront chemotherapy in TCCB are to prove in randomized phase III trials that the addition of toxic chemotherapy to toxic standard locoregional treatment can improve survival and/or permit bladder preservation. If such proof is obtained, we will ne …
The first priorities for upfront chemotherapy in TCCB are to prove in randomized phase III trials that the addition of toxic chemotherapy to …
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